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姓名：陈倩
性别：女
陈倩，中共党员，本科毕业于西北农林科技大学，博士毕业于西安交通大学，目前主要从事生物化学与分子生物专业相关的科学研究。
主要研究方向：
糖脂代谢相关靶分子在非酒精性脂肪肝炎（NASH）中的作用机制研究。
近五年的代表性论文：
1. Qian Chen, Jing Yi, Fangtong Liu, Jing Li, … Shemin Lu, Dongmin Li*, TGF-β1 contributes to the hepatic inflammation in animal models with nonalcoholic steatohepatitis by Smad3/TLR2 signaling pathway[J]. Molecular Immunology, 2022,152:129-139. JCR Q3. IF=4.174/2022.
2. Lina Feng , Yanping Chen , Ke Xu , Yingchao Li, Farooq Riaz , Kaikai Lu , Qian Chen, … Dongmin Li*. Cholesterol-induced leucine aminopeptidase 3 (LAP3) upregulation inhibits cell autophagy in pathogenesis of NAFLD[J]. Aging, 2022,14(7):3259-3275. JCR Q2. IF=5.955/2022.
3. Xiaojuan Du, EK Osoro , Qian Chen , … Shemin Lu*. Pdcd4 promotes lipid deposition by attenuating PPARα- mediated fatty acid oxidation in hepatocytes[J]. Mol Cell Endocrinol, 2022,545:111562. JCR Q2. IF=4.369/2022.
4. Jing Li# , Qian Chen# , Jing Yi, Xi Lan, … Dongmin Li*, Shemin Lu*. IFN-γ contributes to the hepatic inflammation in HFD-induced nonalcoholic steatohepatitis by STAT1β/TLR2 signaling pathway[J]. Molecular Immunology, 2021,134:118-128. JCR Q3. IF=4.407/2021.
5. Farooq Riaz, Qian Chen, Kaikai Lu, Ezra Kombo Osoro, … Dongmin Li*. Inhibition of miR- 188-5p alleviates hepatic fibrosis by significantly reducing the activation and proliferation of HSCs through PTEN/PI3K/AKT pathway[J]. J Cell Mol Med, 2021,25(8):4073-4087. JCR Q2. IF=5.295/2021.
6. Litao Wu, Juan Sun, Li Liu, Xiaojuan Du, Yan Liu, Xiaofei Yan, Ezra Kombo Osoro, Fujun Zhang, Lina Feng, Dong Liang, Yazhao Li, Qian Chen, … Dongmin Li*, Shemin Lu. Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NF-κB pathways[J]. Int Immunopharmacol, 2020,82:106368. JCR Q1. IF= 4.932/2020.
7. Kaiting Ning, Kaikai Lu, Qian Chen, Zizhen Guo, … Dongmin Li*. Epigallocatechin Gallate Protects Mice against Methionine–Choline-Deficient-Diet-Induced Nonalcoholic Steatohepatitis by Improving Gut Microbiota To Attenuate Hepatic Injury and Regulate Metabolism[J]. ACS Omega, 2020 Aug 25;5(33):20800–20809. JCR Q2. IF=3.512/2020.
8. Xi Lan, Litao Wu, Nan Wu, Qian Chen, … Dongmin Li, Shemin Lu*. Long Noncoding RNA lnc-HC Regulates PPARγ-Mediated Hepatic Lipid Metabolism through miR- 130b-3p[J]. Mol Ther Nucleic Acids, 2019,18:954–965. JCR Q1. IF=7.032/2019.
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